IF YOU HAVE CHRONIC HEPATITIS C (HEP C), DAKLINZA MAY BE ABLE TO HELP

STARTING TREATMENT

Starting Daklinza™ (daclatasvir) treatment regimens1

An all-oral treatment (60 mg) that may cureCure Close ButtonCure means that no Hep C virus was detected in the blood when tested 12 weeks after treatment ends.2  chronic Hep C in 12 weeks, in genotypes 1 or 31*

For more information, please visit the About Daklinza page.

How to take Daklinza

  • Take Daklinza exactly how you are told to by your healthcare provider.
  • Do not change your dose unless you are told to by your healthcare provider.
  • Do not stop taking Daklinza without first talking with your healthcare provider.
  • Take Daklinza one time each day with or without food.
  • If you miss a dose, call your healthcare provider or pharmacist. It is important that you do not miss or skip doses of Daklinza during treatment.
  • If you take too much Daklinza, call your healthcare provider or go to the nearest hospital emergency room right away.

Talk to your healthcare provider:

Before you take Daklinza, it is important to tell your healthcare provider about all of your medical conditions, including if you:

  • Have liver problems other than Hep C infection.
  • Have had a liver transplant.
  • Have heart problems.
  • Are pregnant or plan to become pregnant. It is not known if Daklinza will harm your unborn baby.
    • When taking Daklinza in combination with sofosbuvir and ribavirin, tell your healthcare provider right away if you or your female sexual partner becomes pregnant.
    • Males and females who take Daklinza with sofosbuvir and ribavirin should also read the ribavirin Medication Guide for important pregnancy, contraception, and infertility information.
  • Are breastfeeding or plan to breastfeed. It is not known if Daklinza passes into your breast milk.
    • Talk to your healthcare provider about the best way to feed your baby during treatment with Daklinza.

*You should also read the patient information for sofosbuvir and ribavirin.

SELECTED IMPORTANT SAFETY INFORMATION

What are the most common side effects of Daklinza and sofosbuvir?
Headache, tiredness.

What are the most common side effects of Daklinza when used with sofosbuvir and ribavirin?
Headache, low red blood cell count, tiredness, nausea.

These are not all the possible side effects of Daklinza; call your doctor concerning side effects.

References: 1. Daklinza [package insert]. Princeton, NJ: Bristol-Myers Squibb Company. 2. AASLD/IDSA/IAS-USA. When and in whom to initiate HCV therapy. Recommendations for testing, managing, and treating hepatitis C. http://www.hcvguidelines.org/full-report/when-and-whom-initiate-hcv-therapy. Accessed November 19, 2015.
 

IMPORTANT SAFETY INFORMATION

What is the most important information I should know about Daklinza?

  • Daklinza can cause serious side effects, including Hepatitis B virus reactivation. Your healthcare provider will do blood tests to check for hepatitis B virus infection before starting Daklinza. If you have ever had hepatitis B virus infection, the virus could become active again (called reactivation) during or after treatment with Daklinza. This may cause serious liver problems, including liver failure and death. Your healthcare provider will monitor you if you are at risk for hepatitis B virus reactivation during treatment and after stopping Daklinza.

Before taking Daklinza, tell your healthcare provider about all your medical conditions, including if you:

  • Have ever had hepatitis B virus infection; have liver problems other than hepatitis C infection; have had a liver transplant; have heart problems; or if you are pregnant or breastfeeding or plan to become pregnant or breastfeed. It is not known if Daklinza will harm your unborn baby or pass into your breast milk. When taking Daklinza in combination with sofosbuvir and ribavirin, tell your healthcare provider right away if you or your female sexual partner become pregnant. Males and females on this regimen should also read the ribavirin Medication Guide for important pregnancy, contraception, and infertility information.
  • Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Daklinza may affect the way other medicines work, and other medicines may affect how Daklinza works. Do not start taking a new medicine without telling your healthcare provider.
  • Daklinza in combination with sofosbuvir and amiodarone may cause serious side effects, including slow heart rate (bradycardia). Get medical help right away if you take amiodarone with sofosbuvir and Daklinza and get any of the following: fainting or near-fainting, weakness, chest pain, dizziness or lightheadedness, tiredness, confusion, not feeling well, shortness of breath, memory problems.

What are the most common side effects of Daklinza and sofosbuvir?
Headache, tiredness.

What are the most common side effects of Daklinza when used with sofosbuvir and ribavirin?
Headache, low red blood cell count, tiredness, nausea.

These are not all the possible side effects of Daklinza; call your doctor concerning side effects.

Please see Full Prescribing Information, including "What is the most important information I should know about Daklinza?" in the Patient Information section.

 

More Important Safety Information

SELECTED IMPORTANT SAFETY INFORMATION

  • Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Daklinza may affect the way other medicines work, and other medicines may affect how Daklinza works. Do not start taking a new medicine without telling your healthcare provider.